Research

In addition to our commitment to offering the most up-to-date care available for children with diabetes, our providers are also continually conducting research in the field of diabetes. Our faculty study a wide range of topics, including health outcomes and quality of life for children with diabetes, and the link between childhood obesity and its long-term endocrine consequences such as pubertal maturation.

 

U-M faculty also explore ways to improve the tools available to families to support them in managing their child’s diabetes. We focus on providing patients information about the latest diabetes technology (such as insulin brands, pumps, continuous glucose monitors) to allow them to decide if it right for them. See below for additional information about some of our current studies.

If you would like to search for eligible research studies not listed below, click here.

Actively Recruiting Studies

Understanding the Use of Visual Data Stories for Problem-Solving with Type 1 Diabetes Data

Managing Type 1 Diabetes is hard. Together, we can make it easier.

 

If you or your child are living with Type 1 diabetes, we have an opportunity for you to help create novel data interfaces to simplify day-to-day decision-making with T1D data. You will work with researchers over two remote sessions to review novel data interfaces and provide your feedback. At the end of the two sessions, you will earn up to a $80 gift card

 

Who is eligible to participate in this study? (Must meet all criteria)

  • Adults with T1D or Caregivers of children or adolescents with T1D receiving care for T1D at Michigan Medicine

  • Adult or pediatric patients must use CGM and insulin pump

  • Have a laptop with internet connection and camera

  • English speaking

  • Willing to share your diabetes data for research

  • Diagnosed for more than 1 year

What will happen to me in this study?

  • You will participate in two remote sessions via Zoom to review T1D data

  • Researchers will use your diabetes data to create novel data interfaces to aid problem-solving

  • For each session,

    • You will answer questions related to the data​

    • You will take surveys to help researchers understand the cognitive load of reviewing data

    • You will answer questions about your experience of reviewing data

  • Each session will last about 2 hours and will be scheduled at your convenience

If you would like to participate and/or have any questions, please contact Shriti Raj (shritir@umich.edu) or at 734-926-8725.

For more details, please visit: https://umhealthresearch.org/#studies/HUM00196479

Type 1 Diabetes TrialNet Pathway to Prevention Study

Did you know that relatives of people with type 1 diabetes have 15 times greater risk for developing the disease than people with no family history?

 

We are partnering with the University of Michigan TrialNet team to prevent type 1 diabetes and we encourage you to get involved. TrialNet is an international network of researchers seeking ways to delay or prevent type 1 diabetes. TrialNet offers risk screening to relatives of people with type 1 diabetes to see if they are at risk for developing the disease. The screening is a free blood test that can detect the risk for type 1 diabetes years before symptoms appear. Most of this process can be completed from home!

 

How can you get involved?

 

If someone in your family has type 1 diabetes, you can sign up at UMHSTrialNet@med.umich.edu to have a test kit mailed to you, free of charge, to obtain a screening sample. You can order an in-home test kit, or a lab test kit that you take to a lab for the blood draw. Test kits can be mailed to you anywhere in the US and all of the paperwork can be completed electronically. If testing shows that you are at increased risk for type 1 diabetes, you can be monitored by TrialNet and may be eligible to join a research study testing ways to prevent or delay the disease.

 

Who is eligible to be screened?

  • Anyone ages 2.5 through 45 with a sibling, child, or parent with type 1 diabetes.

  • Anyone ages of 2.5 through 20 with a sibling, child, parent, cousin, aunt, uncle, niece, nephew, grandparent or half-sibling with type 1 diabetes.

 

For more information, please call (734) 615-4079 or email Andrea Haddad, MS, CCRP at UMHS-TrialNet@med.umich.edu. We hope to hear from you soon!

Ongoing Research Studies

The Effects of Diet-Induced Obesity on Hematopoiesis

In order to understand the source of inflammation we have focused on understanding changes within the hematopoietic compartment. The prominent white blood cell increased and activated during obesity is the macrophage. We have focused our studies on looking at the generation of myeloid cells (macrophages and neutrophils) and how this is enhanced in the bone marrow of obese mice. These changes are sustained even after bone marrow transplantation and weight loss. By investigating the changes within these progenitors we will gain knowledge and understanding of the long-term persistent impact of diet-induced obesity on the immune system.

For more information, check the Singer Lab research website.