Research
In addition to our commitment to offering the most up-to-date care available for children with diabetes, our providers are also continually conducting research in the field of diabetes. Our faculty study a wide range of topics, including health outcomes and quality of life for children with diabetes, and the link between childhood obesity and its long-term endocrine consequences such as pubertal maturation.
U-M faculty also explore ways to improve the tools available to families to support them in managing their child’s diabetes. We focus on providing patients information about the latest diabetes technology (such as insulin brands, pumps, continuous glucose monitors) to allow them to decide if it right for them. See below for additional information about some of our current studies.
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If you would like to search for eligible research studies not listed below, click here.
Actively Recruiting Studies
Type 1 Diabetes TrialNet Pathway to Prevention Study
Did you know that relatives of people with type 1 diabetes have 15 times greater risk for developing the disease than people with no family history?
We are partnering with the University of Michigan TrialNet team to prevent type 1 diabetes and we encourage you to get involved. TrialNet is an international network of researchers seeking ways to delay or prevent type 1 diabetes. TrialNet offers risk screening to relatives of people with type 1 diabetes to see if they are at risk for developing the disease. The screening is a free blood test that can detect the risk for type 1 diabetes years before symptoms appear. Most of this process can be completed from home!
How can you get involved?
If someone in your family has type 1 diabetes, you can request to have a test kit mailed to you, free of charge, to obtain a screening sample. You can order an in-home test kit or a lab test kit that you take to a lab for the blood draw. Test kits can be mailed to you anywhere in the US and all of the paperwork can be completed electronically. If testing shows that you are at increased risk for type 1 diabetes, you can be monitored by TrialNet and may be eligible to join a research study testing ways to prevent or delay the disease.
Who is eligible to be screened?
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Anyone ages 2 through 45 years old with a sibling, child, or parent with type 1 diabetes (1st degree relatives).
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Anyone ages 2 through 20 years old with a cousin, aunt, uncle, niece, nephew, grandparent, or half-sibling with type 1 diabetes (2nd degree relatives).
For more information, please call (734) 232-4213 or email our Study Coordinator, at UMHS-TrialNet@med.umich.edu. We hope to hear from you soon!
Targeting type 1 Diabetes via Polyamines (TADPOL)
We are conducting a clinical trial for patients with new onset type 1 diabetes. This study is investigating the use of an investigational drug known as DFMO (difluoromethylornithine) which reduces the amount of stress on cells that make insulin and preserves insulin production. Participation in this study will be approximately 12 months.
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Who can participate?
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Individuals between the ages of 6 and 40 years old diagnosed with type 1 diabetes in the past 100 days are eligible to participate in the study.
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There are additional inclusion criteria to participate in the clinical trial that will be determined at screening.
What is involved?
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There are 6 in-person visits and 1 phone visit over a 12-month period.
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If you do not currently wear a Dexcom CGM, you will be provided with one for study participation.
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The in-person visits are approximately 3-4 hours in length. All in-person visits involve a mixed meal tolerance test, blood draw, vital signs, medical and health history review, and CGM download
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Some in-person visits may also involve the following: physical exam, audiology exam, urine specimen, and surveys.
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Compensation is provided for all completed study visits.
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For more information, please contact Aimee Katona, Study Coordinator, at PEDS-DM-ENDO-Research@med.umich.edu, or call (734) 615-4079. We hope to hear from you soon!
Seeking 12-18 year olds with Type 1 Diabetes for Text Message Study
​The QUALITY study team wants to understand how adolescents with type 1 diabetes (T1D) make decisions about their diabetes management through the day. We are seeking 12-18 year olds with T1D who receive care at Michigan Medicine and use a continuous glucose monitor (CGM) to participate in the study.
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For more information, click here.
Seeking 11-21 year olds with Type 1 Diabetes for Text Message Study
The Daily Eating & Diabetes Device Data in Adolescents with T1D study (HUM00253104) is hoping to understand how adolescents with type 1 diabetes (T1D) make decisions about eating and their diabetes throughout the day. Participation in this study lasts about two weeks. ​
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Who can participate?
11–21-year-olds who:
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Receive care at Michigan Medicine and have used a continuous glucose monitor (CGM) and insulin pump for at least 6 months.
What is involved?
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Complete eating surveys 4 times per day for 14 days
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Share 90 days of CGM and insulin pump data
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Complete a one-time interview on Zoom
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Earn up to $320 as a check or gift card in the mail
To learn more show interest in participating, visit: https://redcap.link/EAT-T1D or email Sam Chuisano, Study Coordinator, at fammed-t1d@med.umich.edu or call (734) 936-1927.​
For more information, click here